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About us
Who we are
Our global reach
Gallery of innovation
Expertise
Why Xcenda?
Areas of expertise
Solutions
Commercialization solutions
Innovative field solutions
Health economics & outcomes research
Reimbursement & policy insights
Real-world evidence
FormularyDecisions
Value and access communications
Global market access consulting
Product launch and commercialization
Market research and advisor networks
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Manufacturer solutions from AmerisourceBergen
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Insights home
Health Policy Weekly archive
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HTA Decision Map
Stay informed on key HTA decisions
Use the filters below to find detailed information on product decisions in Australia, Canada, France, Germany, and the United Kingdom.
Product
5-aminolevulinic acid
Abacavir + dolutegravir + lamivudine
Abatacept
Abatacept + methotrexate
Abiraterone
Aclidinium
Aclidinium + eformoterol
Aclidinium + formoterol
Aclidinium bromide
Aclidinium/formoterol
Adalimumab
Afatinib
Aflibercept
Aflibercept + irinotecan + fluorouracil
Agomelatine
Albiglutide
Albutrepenonacog
Aldesleukin (IL-2)
Alectinib
Alemtuzumab
Alglucosidase alfa-rch
Alipogene
Alirocumab
Aliskiren
Aliskiren + amlodipine
Alogliptin
Alogliptin + metformin
Alpha-1 antitrypsin
Alprostadil
Alteplase
Ambrisentan
Amikacin
Amino acid formula without phenylalanine
Aminolevulinic acid
Anidulafungin
Apixaban
Apremilast
Aprepitant
Arginine with carbohydrate
Aripiprazole
Armodafinil
Arsenic
Arsenic trioxide
Asenapine
Asfotase alfa
Asunaprevir
Atazanavir
Atazanavir + cobicistat
Atosiban
Atovaquone + proguanil
Autologous chondrocytes
Axitinib
Azacitidine
Azilsartan
Azilsartan + chlorthalidone
Aztreonam
Beclomethasone
Beclomethasone + formoterol
Bedaquiline
Belatacept
Belimumab
Bendamustine
Benzathine benzylpenicillin
Betaine
Betamethasone + calcipotriol
Bevacizumab
Bevacizumab + gemcitabine + carboplatin
Bimatoprost
Blinatumomab
Boceprevir
Bortezomib
Bosentan
Bosutinib
Botulinum toxin A
Botulinum toxin type A
Brentuximab vedotin
Brexpiprazole
Brimonidine + brinzolamide
Brinzolamide + brimonidine
Brivaracetam
Bromazepam
Budesonide
Budesonide + eformoterol
Busulfan
C1 esterase inhibitor
Cabazitaxel
Cabergoline
Cabozantinib
Calcipotriol + betamethasone
Canagliflozin
Canagliflozin + metformin
Canakinumab
Cangrelor
Carbohydrate with docosahexanoic acid
Carbohydrate with docosahexanoic acid and arachidonic acid
Carbohydrate/ fat/ vitamins/ minerals/ trace elements/ long-chain polyunsaturates (LCPS) arachidonic acid (AA) and docosahexanoic acid (DNA)/ protein-free formula
Carbomer 980
Carfilzomib
Carglumic acid
Carmellose sodium
Ceftazidime + avibactam
Ceftobiprole
Ceftolozane + tazobactam
Cefuroxime
Ceritinib
Certolizumab
Cetuximab
Chloroprocaine
Cholic acid
Ciclopirox
Cinacalcet
Cisatracurium
Clevidipine
Clobetasol propionate
Clotrimazole
Cobicistat
Cobicistat + darunavir
Cobicistat + elvitegravir + emtricitabine + tenofovir
Cobimetinib
Cobimetinib + vemurafenib
Colesevelam
Colestilan
Colistimethate
Colistin
Collagenase clostridium histolyticum
Corifollitropin alfa
Crisantaspase
Crizotinib
Cyclosporine
Cytarabine
Dabigatran
Dabrafenib
Dabrafenib + trametinib
Daclatasvir
Daclizumab
Dalbavancin
Dapagliflozin
Dapagliflozin + insulin
Dapagliflozin + metformin
Dapagliflozin + metformin XR
Daratumumab
Darunavir
Darunavir + cobicistat
Darunavir/cobicistat
Dasabuvir
Dasatinib
Daunorubicin
Decitabine
Deferasirox
Defibrotide
Degarelix
Degludec insulin + liraglutide
Delamanid
Denosumab
Desogestrel
Dexamethasone
Dexamethasone + ciprofloxacine
Dexamethasone intravitreal implant
Dexketoprofen + tramadol
Dextromethorphan bromhydrate
Diazepam
Dienogest
Dimethyl fumarate
Dimethyl fumarate (DMF)
Docetaxel
Dolutegravir
Donepezil
Dorzolamide + timolol
Doxorubicin
Doxycycline
Droperidol
Dulaglutide
Econazole
Eculizumab
Edoxaban
Efmoroctocog alfa
Eftrenonacog
Elbasvir + grazoprevir
Eliglustat
Elosulfase alfa
Elotuzumab
Eltrombopag
Elvitegravir + cobicistat + emtricitabine + tenofovir alafenamide
Elvitegravir + cobicistat + emtricitabine + tenofovir disoproxil
Empagliflozin
Empagliflozin + linagliptin
Empagliflozin + metformin
Emtricitabine + rilpivirine + tenofovir
Emtricitabine + tenofovir
Enzalutamide
Epinephrine
Eplerenone
Epoprostenol
Eribulin
Erlotinib
Erythropoiesis-stimulating agents (epoetin and darbepoetin)
Eslicarbazepine acetate
Esomeprazole
Estradiol hemihydrate + dydrogesterone
Etanercept
Etanercept (biosimilar)
Ethinylestradiol + levonorgestrel
Ethyl esters of iodized fatty acids
Ethyl loflazepate
Everolimus
Everolimus + exemestane
Evolocumab
Exenatide
Extract from cannabis
Ezetimibe
Ezetimibe + atorvastatin
Ezetimibe + rosuvastatin
Ezetimibe + simvastatin
Fampridine
Fenofibrate + simvastatin
Fentanyl
Fentanyl nasal spray
Fentanyl sublingual tablet
Ferric carboxymaltose
Fesoterodine
Fidaxomicin
Filgrastim
Filgrastim (biosimilar)
Fingolimod
Florbetapir
Fluocinolone
Fluorouracil + salicylic acid
Fluticasone
Fluticasone + eformoterol
Fluticasone + formoterol
Fluticasone + vilanterol
Fluticasone furoate + vilanterol trifenatate
Follitropin alfa
Follitropin alfa + lutropin alfa
Formoterol + beclomethasone
Furosemide
Gadobutrol
Gadodiamide
Galantamine
Gefitinib
Gemcitabine
Glucosamine
Glycerol phenylbutyrate
Glycopyrronium bromide
Golimumab
Gonadotrophin
Grass pollen allergen extract
Grazoprevir + elbasvir
Guanfacine hydrochloride
Homatropine hydrobromide
Human prothrombin complex concentrate
Hydrocortisone
Ibrutinib
Icodextrin
Idarucizumab
Idebenone
Idelalisib
Imatinib
Imiquimod
Immunoglobulin human
Incobotulinumtoxin A
Indacaterol
Indacaterol + glycopyrronium
Indapamide + amlodipine
Infliximab
Infliximab (biosimilar)
Infliximab + adalimumab + golimumab (TNF-alpha inhibitors)
Ingenol mebutate
Insulin (implantable)
Insulin aspart
Insulin degludec
Insulin degludec + liraglutide
Insulin detemir
Insulin glargine
Interferon beta-1a
Iopromide
Ipilimumab
Irinotecan
Isavuconazole
Ivabradine
Ivacaftor
Ivacaftor + lumacaftor
Ivermectin
Ixekizumab
Japanese encephalitis vaccine
Lacosamide
Lanreotide
Lapatinib
Latanoprost
Ledipasvir + sofosbuvir
Lenalidomide
Lenvatinib
Letrozole
Leuprorelin
Levetiracetam
Levofloxacin
Levonorgestrel
Levosimendan
Lidocaine + prilocaine
Linaclotide
Linagliptin
Linagliptin + metformin
Linezolid
Lipegfilgrastim
Liraglutide
Lisdexamfetamine
Lixisenatide
Lomitapide
Long-chain triglycerides (LCTs)
Loratadine
Loxapine
Lubiprostone
Lumacaftor + ivacaftor
Lurasidone
Macitentan
Mannitol
Maraviroc
Measles, mumps, rubella, and varicella vaccine
Medium-chain triglycerides (MCTs)
Megestrol
Meglumine amidotrizoate
Memantine
Meningococcal vaccine
Mepolizumab
Mercaptopurine
Meropenem
Mesna
Methylnaltrexone
Methylphenidate
Mifepristone
Mifepristone + misoprostol
Migalastat
Milnacipran
Mirabegron
Misoprostol
Mometasone
Mometasone + formoterol
Multicomponent meningococcal group B vaccine
Mycophenolate
Nabiximols
Nab-paclitaxel
Nadroparin
Nalmefene
Naloxegol
Naproxen
Nebivolol
Necitumumab
Netupitant + palonosetron
Nicotinamide
Nicotine
Nilotinib
Nintedanib
Nitisinone
Nivolumab
Nivolumab + ipilimumab
Obeticholic
Obinutuzumab
Ocriplasmin
Octocog alfa
Octreotide
Ofatumumab
Olanzapine
Olaparib
Olmesartan + amlodipine + hydrochlorothiazide
Olodaterol
Omalizumab
Ombitasvir + paritaprevir + ritonavir
Ombitasvir + paritaprevir + ritonavir ± dasabuvir
Onabotulinumtoxin A
Optaflu
Oritavancin
Osimertinib
Ospemifene
Oxybutynin
Oxycodone + naloxone
Oxytocin
Paclitaxel
Paclitaxel nanoparticle albumin-bound
Palbociclib
Palivizumab
Palonosetron
Palonosetron + netupitant
Panitumumab
Panobinostat
Para-aminosalicylic acid
Paracetamol
Paritaprevir + ritonavir + ombitasvir + dasabuvir
Paritaprevir + ritonavir + ombitasvir + dasabuvir + ribavirin
Pasireotide
Pasireotide diaspartate
Pazopanib
Pegaspargase
Peginterferon alfa + ribavirin
Peginterferon alfa-2a
Peginterferon beta-1a
Pegloticase
Pegvisomant
Pembrolizumab
Pemetrexed
Perampanel
Perempanel
Perindopril + amlodipine
Pertuzumab
Phleum pratense
Pirfenidone
Pitolisant
Pivmecillinam
Pixantrone
Plerixafor
Pneumococcal vaccine
Pomalidomide
Ponatinib
Potassium iodate
Povidone iodine
Pralatrexate
Prasugrel
Prasugrel + percutaneous coronary intervention (PCI)
Pregabalin
Prevenar 13
Progesterone
Propiverine
Propranolol
Protein formula with carbohydrate, fat, fiber, vitamins, and minerals
Protein hydrolysate formula
Prucalopride
Quetiapine
Radium-223
Raltegravir
Ramucirumab
Ranibizumab
Rasagaline
Regadenoson
Regorafenib
Regorafinib
Remifentanil
Reserpine + bendroflumethiazide
Reslizumab
Ribavirin
Rifaximin
Rilpivirine
Riociguat
Risedronate
Rituximab
Rituximab + glucocorticoids
Rivaroxaban
Rivastigmine
Rocuronium
Romidepsin
Romiplostim
Rotavirus vaccine
Rotigotine
Rufinamide
Rupatadine
Ruxolitinib
Sacubitril + valsartan
Safinamide
Salmeterol + fluticasone
Sapropterin
Sarilumab
Saxagliptin
Saxagliptin + metformin
Saxagliptin + metformin XR
Secukinumab
Selexipag
Silodosin
Siltuximab
Simeprevir
Simoctocog alfa
Simvastatin
Sipuleucel-T
Sitagliptin
Sitagliptin + metformin
Sitagliptin + Metformin XR
Sitagliptin + simvastatin
Sodium phenylbutyrate
Sodium sulfate + magnesium sulfate + potassium sulfate
Sofosbuvir
Sofosbuvir + velpatasvir
Somatropin
Sonidegib
Sorafenib
Stiripentol
Strontium
Succimer
Sucroferric oxyhydroxide
Sufentanil
Sunitinib
Tafamidis
Tafluprost
Tafluprost + timolol
Talimogene
Talimogene laherparepvec
Tamoxifen
Tapentadol
Tedizolid
Teduglutide
Telaprevir
Temocillin
Temozolomide
Tenofovir
Tenofovir + emtricitabine
Tenofovir alafenamide
Teriflunomide
Tesamorelin
Tetrabenazine
Tetradecyl
Thiamine
Thiocolchicoside
Ticagrelor
Tinzaparin
Tiotropium
Tiotropium + olodaterol
Tobramycin
Tocilizumab
Tolvaptan
Topotecan
Trabectedin
Trametinib
Trandolapril + verapamil
Trastuzumab
Trastuzumab emtansine
Treprostinil
Trifluridine + tipiracil
Trimethoprim
Triptorelin
Turoctocog alfa
Ulipristal
Ulipristal acetate
Umeclidinium
Umeclidinium + vilanterol
Umeclidinium bromide
Umeclidinium bromide + vilanterol trifenatate
Umeclidinium/vilanterol
Ursodeoxycholic acid
Ustekinumab
Vandetanib
Varenicline
Vaseline + paraffin + lactulose
Vedolizumab
Velaglucerase alfa
Vemurafenib
Venetoclax
Venlafaxine
Vernakalant
Vildagliptin
Vildagliptin + metformin
Vinflunine
Vinorelbine
Vismodegib
von Willebrand factor + coagulation factor VIII
Vorapaxar
Voriconazole
Vorinostat
Vortioxetine
Zoledronic acid
Zolpidem
Zonisamide
Zoster virus vaccine live
Therapeutic Area
Thyroid cancer
Acromegaly
Actinic keratosis (AK)
Acute coronary syndrome (ACS)
Acute cystitis
Acute lymphoblastic leukemia (ALL)
Adenocarcinoma
Adrenal insufficiency
Age-related macular degeneration (AMD)
Alcohol dependence
Alimentary tract disorders
Allergic rhinitis
Alzheimer's disease
Anaphylaxis
Anemia
Anesthesia
Angiomyolipomas
Ankylosing spondylitis (AS)
Anovulation
Anterior uveitis
Anticoagulant reversal
Antisepsis
Anxiety
Arthritis
Assisted reproduction
Asthma
Atrial fibrillation
Attention deficit hyperactivity disorder (ADHD)
Atypical hemolytic uremic syndrome (aHUS)
Axial spondyloarthritis
Basal cell carcinoma (BCC)
Benign prostatic hyperplasia (BPH)
Bile acid synthesis
Biliary cholangitis
Bipolar disorder
Bleeding treatment / prophylaxis
Blepharospasm
Bone cancer
Bowel prep
Branch retinal vein occlusion (BRVO)
Breast cancer
C. difficile infection (CDI)
Candidosis and dermatophytes
Cartilage lesions
Cervical cancer
Cervical dystonia
Chemotherapy toxicity
Choroidal neovascularization
Chronic immune (idiopathic) thrombocytopenic purpura (ITP)
Chronic inflammatory demyelinating polyneuropathy
Chronic iron overload
Chronic kidney disease
Chronic lymphocytic leukemia (CLL)
Chronic myelogenous leukemia (CML)
Chronic myelogenous leukemia (CML)/ acute lymphoblastic leukemia (ALL)
Chronic obstructive pulmonary disease (COPD)
Chronic spasticity
Clinically isolated syndrome (CIS) (pre-multiple sclerosis)
Colorectal cancer (CRC)
Constipation
Contraception
Contrast agent
Cough
Crohn's disease (CD)
Cryopyrin-associated periodic syndrome (CAPS)
Cushing's disease
Cystic fibrosis (CF)
Cystitis
Deep vein thrombosis (DVT)
Depression
Dermatoses
Diabetes mellitus
Diabetes mellitus, Type 1 (T1DM)
Diabetes mellitus, Type 2 (T2DM)
Diagnostics
Dry eye disease
Dupuytren's contracture
Emphysema
Encephalitis
Endophthalmitis
Epilepsy
Erectile dysfunction
Fabry disease
Familial hypercholesterolemia
Fertility
Fibromyalgia
Follicular lymphoma (FL)
Fungal infections
Gastroenteritis
Gastroesophageal reflux disease (GERD)
Gastrointestinal cancer
Gaucher disease
General anesthesia
Glaucoma
Glioblastoma
Gout
Granulomatosis
Growth hormone deficiency
Head and neck cancer
Heart failure
Hemangiomas
Hemophilia A
Hepatic disease
Hepatic encephalopathy (HE)
Hepatitis
Hepatitis B (HBV)
Hepatitis C (HCV)
Hereditary angioedema
Herpes zoster
Hidradenitis suppurativa (HS)
Homocystinuria
Hormone replacement therapy (HRT)
Human immunodeficiency virus (HIV)
Huntington's chorea
Hyperammonemia
Hypercalcemia of malignancy
Hypercholesterolemia / hyperlipidemia
Hyperparathyroidism
Hyperphenylalaninemia
Hyperphosphatemia
Hypertension (HTN)
Hyponatremia
Hypophosphatasia
Inadequate uterine contractions
Infantile hemangioma (IH)
Infectious disease
Infertility
Insomnia
Iodine deficiency
Iron deficiency anemia (IDA)
Irritable bowel syndrome with constipation (IBS-C)
Juvenile idiopathic arthritis (JIA)
Kaposi's sarcoma
Kidney disease
Kidney transplant
Labor induction
Lead and mercury poisoning
Leber's disease
Lennox-Gastaut syndrome
Leukemia
Lipoprotein lipase deficiency
Liposarcoma or leiomyosarcoma
Liver cancer
Liver disease
Liver transplantation
Local anesthesia
Lung cancer
Lupus nephritis
Luteinizing hormone (LH) deficiency
Lymphoma
Lymphoma and myeloma
Macular degeneration
Macular edema
Malignant glioma
Malnutrition
Mantle cell lymphoma (MCL)
Medicinal food
Medullary thyroid cancer (MTC)
Melanoma
Metabolite disorders
Migraine
Miscarriage
Mucopolysaccharidosis IVA (Morquio A syndrome)
Multicentric Castleman's disease (MCD)
Multiple myeloma
Multiple myeloma / lymphoma
Multiple sclerosis (MS)
Myelodysplastic syndrome (MDS)
Myelofibrosis
Myeloid leukemia
Myeloma
Myopia
Narcolepsy
Nausea and vomiting
Neuroendocrine tumors (NETs)
Neuropathic pain
Neutropenia
Non-Hodgkin's lymphoma (NHL)
Non-small cell lung cancer (NSCLC)
Ophthalmology
Opioid-induced constipation
Organ transplantation
Osteoarthritis
Osteoporosis
Otitis externa (OE) and otorrhea
Ovarian cancer
Ovarian, fallopian, or peritoneal cancer
Overactive bladder
Pain
Painful muscle contractures
Pancreatic cancer
Pancreatic neuroendocrine tumor (pNET)
Parkinson's disease
Paroxysmal nocturnal hemoglobinuria (PNH)
Peritoneal dialysis
Phenylketonuria (PKU)
Plaque psoriasis
Plasmodium falciparum malaria
Polycystic kidney disease
Polycythemia vera
Pompe disease
Post-stroke upper limb spasticity
Precocious puberty
Pregnancy termination
Premature labor
Proliferating infantile hemangioma
Prostate cancer
Psoriasis
Psoriatic arthritis (PsA)
Pulmonary arterial hypertension (PAH)
Pulmonary fibrosis
Pulmonary hypertension
Renal cell carcinoma (RCC)
Renal failure
Respiratory syncytial virus (RSV)
Restless legs syndrome
Rheumatoid arthritis (RA)
Rosacea
Scabies
Schizophrenia
Schizophrenia and bipolar disorder
Seborrheic dermatitis
Sedation
Short bowel syndrome (SBS)
Smoking cessation
Social anxiety disorder
Soft tissue sarcoma
Splenomegaly
Spondyloarthritis
Stem cell transplant
Stroke
Stroke and venous thromboembolism (VTE)
Subfoveal choroidal neovascularization
Suppurative hidradenitis
Systemic lupus erythematosus (SLE)
Thiamine deficiency
Thrombocytopenia
Transitional cell carcinoma (TCC)
Transthyretin amyloidosis
Tuberculosis (TB)
Tuberous sclerosis (TS)
Turner syndrome (TS)
Tyrosinemia
Ulcerative colitis (UC)
Urea cycle disorder
Urea disorders
Urinary incontinence
Urticaria
Uterine fibroids
Uveitis
Vaccination
Vaginal atrophy
Vaginal infection
Vasculitis
Vein occlusion
Venous thromboembolism (VTE)
Visceral adipose tissue (VAT)
Visual impairment due to diabetic macular edema (DME)
Visual impairment due to macular edema secondary to retinal vein occlusion (RVO)
Vitamin B₃ (PP) deficiency
Vitreomacular adhesion (VMA)
Vitreomacular traction (VMT)
von Willebrand disease
Waldenström's macroglobulinemia (WM)
Country
Australia (PBAC)
Canada (CADTH)
France (HAS)
Germany (IQWiG)
UK (NICE)
Year
2012
2013
2014
2015
2016
2017
Decision
Favorable
Mixed
Neutral
Unfavorable
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Therapeutic Area
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